Lenvatinib Trade name: Lenvima™
Lenvatinib is the generic for the trade name drug Lenvima™. In some cases, health care professionals may use the trade name Lenvima™ when referring to the generic drug name lenvatinib.
Drug type: Lenvatinib is a targeted therapy. It is an oral receptor tyrosine kinase inhibitor
What this drug is used for:
- For the treatment of patients with locally recurrent or metastatic, progressive, radioactive iodine-refractory differentiated thyroid cancer.
Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.
How this drug is given:
- Lenvatinib is a pill, taken by mouth, once daily. It can be taken with or without food.
- Take lenvatinib exactly as prescribed.
- Swallow lenvatinib capsules whole. Do not crush, dissolve or open capsules.
- Do not change your dose or stop lenvatinib unless your health care provider tells you to.
- If you miss a dose, take it as soon as you remember. If your next dose is within 12 hours, skip the missed dose and take the next dose at your regular time.
- Do not take more than 1 dose of lenvatinib at one time. Call your health care provider right away if you take too much.
- The amount of lenvatinib that you will receive depends on many factors, your general health or other health problems, and the type of cancer or condition being treated.
- Dose modifications are often made so it is important to let your healthcare provider know of any side effects.
Important things to remember about the side effects of lenvatinib:
- Most people do not experience all of the side effects listed.
- Side effects are often predictable in terms of their onset and duration.
- There are many options to help minimize or prevent side effects.
- There is no relationship between the presence or severity of side effects and the effectiveness of the medication.
The following side effects are common (occurring in greater than 30%) for patients taking lenvatinib:
- High blood pressure
- Joint/muscle aches
- Decreased appetite
- Weight loss
- Stomatitis (mouth sores)
- Proteinuria (protein in the urine)
- Palmar-plantar erythrodysesthesia (hand-foot syndrome)
- Abdominal pain
- Dysphonia (difficulty speaking)