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Emonat -Temozolomide temonat contains temozolomide and belongs to a class of drugs known as imidazotetrazine derivatives.   Indication temonat is used for the treatment of certain types of brain cancers (e. G. , refractory anaplastic astrocytoma).   Mechanism of action temonat slows or stops the growth and spread of cancer cells in your body. Supplied as temonat is available as 20mg, 100mg & 250mg capsules.   Dosage the recommended dose of temonat is usually once daily for 5 days. The treatment may be repeated every 28 days.   Overdose symptoms of overdose associated with temonat may include chills, persistent sore throat or persistent fever; or severe bleeding or bruising.   Precautions & Warnings temonat should not be taken without consulting your doctor if you have kidney disease, liver disease, blood disorders such as low white blood cell counts or low blood platelet levels, allergies (especially to dacarbazine). Temonat may lower the body's ability to fight an infection. Do not take temonat if you are allergic to it or to any ingredient in temonat and to dacarbazine. do not take temonat without consulting your doctor if you are pregnant   Drug Interactions the following drugs may interact with temonat:
  • the risk of severe infection may be increased by corticosteroids (e. G. , prednisone)
  • the risk of temonat 's side effects may be increased by valproic acid
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