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Description

Brand Name:

Hycamtin

Generic Name:

Hycamtin

Company:

Glaxo

Strength:

1mg

Packing:

1X10

Type:

Capsule

Use:

Anti Cancer Drugs



Hycamtin binds to the topoisomerase I-DNA complex and prevents religation of these single strand breaks. This ternary complex interferes with the moving replication fork, which leads to the induction of replication arrest and lethal double-stranded breaks in DNA. The formation of this ternary complex eventually leads to apoptosis (programmed cell death).

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